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ea0056gp8 | Acromegaly | ECE2018

ACRONIS, a European observational study in patients with uncontrolled acromegaly who are being treated with long acting pasireotide: first interim analysis

Schofl Christof , Colao Annamaria , Neggers SJCMM , Feldt-Rasmussen Ulla , Moreno Eva Maria Venegas , Enderle Gesine , Mesenska Daniela , Andry Philippe , Tabarin Antoine

Acromegaly is a morbid condition mainly caused by overproduction of growth-hormone (GH) from a pituitary adenoma leading to excessive growth. Normalisation of insulin-like growth factor-1 (IGF1) is an important goal for the treatment of acromegaly. The second-generation somatostatin analog (SSA) long acting pasireotide (la-PAS) has recently been introduced for the management of patients uncontrolled by first-generation SSA. The ACRONIS study (CSOM230CIC05) will provide real-wo...

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ea0037ep789 | Pituitary: clinical | ECE2015

Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel^® treatment in acromegaly patients in routine clinical practice

Escola Cristina Alvarez , Moreno Eva Maria Venegas , Arnes Juan Antonio Garcia , Carrera Concepcion Blanco , Azpiroz Monica Marazuela , Moreno Maria Angeles Galvez , Torre Edelmiro Menendez , Pardo Javier Aller , Vert Isabel Salinas , Resmini Eugenia , Vela Elena Maria Torres , Redondo Maria Angeles Gonzalo , Joya Ricardo Vilchez , Novoa Maria Paz de Miguel , Rabinovich Irene Halperin , Fernandez Concepcion Paramo , Alfonso Antonio Miguel Pico , Arroyo Sara , Perez Francesc , Pineda Eva

Introduction: This study aimed to determine the timeframe to achieve hormonal normalization considering dosing patterns of Somatuline Autogel (SOM, lanreotide) used in clinical practice.Methods: From March 2013 to October 2013 clinical data from 62 patients with active acromegaly treated with SOM for &gE;4 months who achieved hormonal control (GH levels <2.5 ng/ml and/or normalised IGF1 on &gE;two evaluations) at 17 Spanish hospitals were collected i...

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Endocrine Abstracts

ACRONIS, a European observational study in patients with uncontrolled acromegaly who are being treated with long acting pasireotide: first interim analysis

Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel^® treatment in acromegaly patients in routine clinical practice

BiosciAbstracts

Endocrine Abstracts

ACRONIS, a European observational study in patients with uncontrolled acromegaly who are being treated with long acting pasireotide: first interim analysis

Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel® treatment in acromegaly patients in routine clinical practice

BiosciAbstracts

Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel^® treatment in acromegaly patients in routine clinical practice